If you have not had chickenpox but come into contact with someone who has chickenpox or shingles, or if you develop chickenpox or shingles, you should stop leflunomide and see your doctor immediately as you may need special treatment. Arava, generic kobe billig leflunomide med dr. recept drug name leflunomide, is DMARD disease-modifying anti-rheumatic drug used in the treatment of arthritis. Leflunomide was statistically significantly superior to placebo in reducing the signs and symptoms of RA by the primary efficacy analysis, ACR20 Responder at Endpoint, in study US301 at the primary 12 months endpoint and MN301 at month endpoint.